Methylcyclopropene-PEG3-Mal

Methylcyclopropene-PEG3-Mal / Methylcyclopropene-PEG3-Maleimide: Overview and Applications

Product Summary
Methylcyclopropene-PEG3-Mal (or Methylcyclopropene-PEG3-Maleimide) is a specialized bioconjugation linker featuring a methylcyclopropene group and a maleimide group, connected by a PEG3 spacer. The methylcyclopropene group participates in bioorthogonal reactions, while the maleimide group reacts efficiently with thiol groups, enabling targeted and stable conjugations. This linker is commonly used in applications that require precise and selective bonding.

Applications of Methylcyclopropene-PEG3-Maleimide

1. Antibody-Drug Conjugates (ADCs)
   • Facilitates stable drug attachment to antibodies, ideal for ADC development.
2. Targeted Drug Delivery
   • Enhances targeted conjugation with specific biomolecules, aiding in drug delivery systems.
3. Biomolecule Labeling
   • Allows labeling of proteins, peptides, or nucleic acids through selective thiol-maleimide reactions.
4. Surface Modification
   • Suitable for modifying surfaces with bioactive molecules, which is valuable in biosensors and diagnostics.
5. Click Chemistry Applications
   • The methylcyclopropene group enables fast and efficient bioorthogonal click reactions in complex environments.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.