DOTA(OtBu)₃, 137076-54-1, is a modified chelating agent with three tert-butyl (OtBu) ester groups. It binds metal ions like gadolinium and indium, making it ideal for radiopharmaceuticals, bioconjugation, and imaging applications.
Key Features and Uses:
- Chelation: Binds metals securely, providing stability in imaging and therapeutic compounds.
- Protection: The tert-butyl groups protect carboxylic acids, enhancing reactivity for further modification.
- Bioconjugation: Commonly used to attach metals to antibodies or peptides for targeted imaging and treatment.
- Radiopharmaceuticals: Plays a crucial role in MRI, PET scans, and radiotherapy by enabling precise metal attachment.
Handling Tips:
- Storage: Keep it in a cool, dry place, away from light and moisture.
- Safety: Use proper protective gear to handle safely.
DOTA(OtBu)₃ is vital in diagnostics and molecular imaging, especially in nuclear medicine and targeted cancer therapy.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
