OPSS-PEG-NH2, MW 5K possesses two key functional groups: an ortho-pyridyl disulfide (OPSS) group and an amino (NH2) group. The OPSS group is highly reactive with thiols, forming disulfide bonds, while the NH2 group is a primary amine that can participate in a wide range of reactions, such as amide bond formation.
The PEG moiety is a biocompatible, water-soluble polymer consisting of repeating ethylene glycol units. It is known for its stealth properties, reducing immunogenicity and enhancing the solubility of attached biomolecules. With a molecular weight of 2K, this moderately-sized PEG chain ensures a balance between solubility, biocompatibility, and reactivity.
The applications of OPSS-PEG-NH2, MW 5K in medicine are diverse and encompass drug delivery, diagnostics, and biomaterials. Its reactive groups enable conjugation to a variety of molecules, such as proteins, peptides, or antibodies, while the PEGylation enhances their pharmacokinetics and stability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.