Fmoc-NH-PEG-Mal, MW 6K contains a maleimide functional group (-Mal) at the end of a PEG chain, which is protected by the Fmoc group.
Fmoc-NH-PEG-Mal, MW 6K has been extensively used in the development of targeted drug delivery systems. The maleimide group can be used to covalently attach targeting ligands, such as antibodies or peptides, to the PEG chain via a thiol-maleimide reaction. This enables the specific delivery of drugs to targeted cells or tissues, improving therapeutic efficacy and reducing systemic toxicity.
In addition to drug delivery, Fmoc-NH-PEG-Mal has also been utilized in the development of diagnostic tools. The maleimide group can be used to immobilize fluorescent dyes or imaging agents onto the PEG chain, allowing for the visualization of disease states or the monitoring of therapeutic responses.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
