LA-PEG-Mal(Lipoic acid-PEG-Maleimide), MW 3.4K polymer is a chemical compound that is commonly used in pharmaceutical research and development. This compound is a polyethylene glycol (PEG) derivative that contains a lipoic acid group and a maleimide functional group.
The lipoic acid group, which is attached to the PEG chain, is known for its antioxidant properties and ability to scavenge free radicals. The maleimide functional group, on the other hand, is known for its ability to react specifically with sulfhydryl (-SH) groups on proteins and peptides through thiol-maleimide chemistry. This property makes Lipoic acid-PEG-Maleimide, MW 3.4K polymer a valuable tool in the field of drug delivery and pharmaceutical research.
Lipoic acid-PEG-Maleimide, MW 3.4K polymer is often used as a crosslinking agent for conjugation of proteins and peptides to PEG-based drug delivery systems. The maleimide functional group selectively reacts with thiol groups on the target molecule, allowing for controlled conjugation and formation of stable linkages. This approach has been used to develop targeted drug delivery systems that selectively deliver drugs to specific tissues or cells, leading to improved therapeutic efficacy and reduced side effects.
In addition, Lipoic acid-PEG-Maleimide, MW 3.4K polymer has also been employed as a surface modifier for biomedical devices and implants. Its antioxidant properties and ability to react with thiol groups make it a valuable tool for improving biocompatibility and reducing immune response.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.