m-PEG2-NHS ester CAS:1127247-34-0 water-soluble compound contains two critical functional groups: an NHS (N-hydroxysuccinimide) ester group, which reacts selectively with primary amines, and a hydrophilic m-PEG (methoxy polyethylene glycol) spacer which enhances solubility and imparts stealth properties.
m-PEG2-NHS ester facilitates efficient conjugation of PEG to proteins, peptides, and other biomolecules, thereby improving their pharmacokinetic properties, stability, and solubility, while reducing immunogenicity. Applications of m-PEG2-NHS ester include PEGylation of therapeutic proteins or peptides, antibody-drug conjugates (ADCs), and surface modification of nanoparticles for targeted drug delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
