(TMS-methylcyclopropenyl)methyl 4-nitrophenyl carbonate is a type of small molecule linker that contains several functional groups, including a carbonate group, a nitrophenyl group, and a TMS (trimethylsilyl) group.
Small molecule linkers are used in the development of bioconjugates and prodrugs, which are biologically inactive compounds that can be converted into active drugs in the body. The linker serves as a bridge between the drug and a targeting molecule, such as an antibody, peptide, or nucleic acid.
In the case of (TMS-methylcyclopropenyl)methyl 4-nitrophenyl carbonate, the carbonate group can be used to react with a hydroxyl group on a targeting molecule, forming a covalent bond. The TMS group can act as a protecting group, preventing unwanted reactions during the synthesis of the linker. The nitrophenyl group can be used as a cleavable group, enabling the release of the active drug in the body.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
