Methylcyclopropene-PEG3-amine (CAS: 2749286-00-6): Overview and Applications
Product Summary
Methylcyclopropene-PEG3-amine is a versatile linker for bioconjugation and drug delivery, featuring a cyclopropene for site-specific labeling, an amine for stable bonding, and a PEG chain to enhance solubility and biocompatibility, making it ideal for complex biological settings.
Applications
- Antibody-Drug Conjugates (ADCs)
- Attaches drugs stably to antibodies, aiding precise therapeutic targeting.
- Targeted Drug Delivery
- Enables selective drug conjugation, improving precision in delivery systems.
- Biomolecule Labeling
- Labels proteins, peptides, and nucleic acids for accurate tracking and detection.
- Surface Modification
- Modifies surfaces with bioactive molecules, boosting biosensor and diagnostic performance.
- Click Chemistry Reactions
- The cyclopropene group performs CuAAC reactions with azide molecules, enabling efficient, site-specific labeling.
- PEG Chain Benefits
- The PEG3 spacer increases solubility, reduces immune response, and prolongs circulation time, essential for drug and nanoparticle delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.