Propargyl-PEG5-beta-D-glucose CAS:1397682-63-1 is a small molecule linker that is composed of several functional groups, including a propargyl group, a PEG (polyethylene glycol) chain, and a beta-D-glucose moiety. The propargyl group is an alkyne functional group that can undergo click chemistry reactions with azide groups to form stable triazole linkages. The PEG chain improves the solubility and biocompatibility of the linker, while the beta-D-glucose moiety can be used to target specific cells or tissues that express glucose transporters or receptors.
In biomedical applications, Propargyl-PEG5-beta-D-glucose can be used to modify the surface of drugs, nanoparticles, or biomolecules, allowing for targeted delivery to specific cells or tissues. The click chemistry reaction between the propargyl group and azide groups can be controlled and reversible, which can improve the pharmacokinetics and efficacy of drugs, as well as reduce their toxicity and immunogenicity. Additionally, the use of the beta-D-glucose moiety can enable the specific targeting of cancer cells, which often overexpress glucose transporters.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
