6-Azide-Trehalose (6-TreAz) is a modified trehalose molecule with an azide group at the 6th carbon position. This modification enables bioorthogonal “click chemistry” reactions, allowing selective labeling and tracking of trehalose metabolism in biological systems. Researchers widely use 6-TreAz to study sugar uptake, distribution, and metabolism in cells, especially in microbial and cellular research.
Key Features:
- Azide Group: Enables selective “click chemistry” with alkyne-functionalized probes for specific labeling and detection.
- Trehalose Analog: Mimics natural trehalose, allowing it to be metabolized or recognized by cellular enzymes, making it ideal for metabolic studies.
- Versatile Detection Methods: Compatible with fluorescence microscopy, flow cytometry, and mass spectrometry for detailed metabolic tracking.
Applications:
- Metabolic Labeling: Used to track sugar metabolism and uptake in cells, especially in microbial studies.
- Bioorthogonal Labeling: Enables specific tagging of trehalose pathways using “click chemistry.”
- Cellular Imaging and Analysis: Suitable for imaging sugar distribution and metabolism in live cells through fluorescence and other detection methods.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
