DSPE-PEG5-azide
This product is an amphiphilic conjugate combining a DSPE lipid anchor, a PEG5 spacer, and a terminal azide group. The DSPE moiety enables stable incorporation into lipid bilayers, micelles, and liposomes, while the PEG5 spacer improves hydrophilicity and steric stabilization. The azide group supports copper-catalyzed (CuAAC) or copper-free (SPAAC) click chemistry with alkynes, making this reagent especially versatile for nanomedicine, drug delivery, and bioconjugation.
Key Features and Benefits
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DSPE Lipid Anchor: Incorporates into lipid membranes, micelles, and liposomes.
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PEG5 Spacer: Provides hydrophilicity, flexibility, and steric stabilization.
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Azide Group: Enables CuAAC or SPAAC click chemistry with alkynes.
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Amphiphilic Design: Combines lipid anchoring with reactive PEG functionality.
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High Purity: Produced to ≥95% purity for reproducible results.
Applications
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Drug Delivery: Functionalizes liposomes and nanoparticles for targeted therapies.
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Nanotechnology: Introduces clickable groups into micelles and lipid-based systems.
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Bioconjugation: Links lipid assemblies with alkyne-modified biomolecules.
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Probe Development: Builds functional lipid–probe conjugates for imaging and diagnostics.
Storage and Handling
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Storage: Store at –20 °C in a sealed, desiccated container.
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Handling: Use freshly prepared solutions; protect from light and moisture.
This product integrates a lipid anchor with PEG5 spacing and azide reactivity, specifically providing a powerful tool for nanomedicine, click chemistry, and advanced lipid–biomolecule conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
