DMTr-PEG12-Azide is a linker containing a dimethoxytrityl-protected alcohol and an azide group. Dimethoxytrityl (DMTr) can be removed by a weak acid. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer can increase solubility in aqueous media.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
