Tisotumab (CAS 1418628-81-5) is a human IgG1 monoclonal antibody that targets tissue factor (TF), a protein found on tumor cells. It binds to TF, inhibiting tumor growth and enhancing immune destruction of the cells.
Key Features:
- Target Specificity: Binds to TF on tumor cells.
- Mechanism of Action: Inhibits tumor growth and boosts immune-mediated destruction.
- Molecular Characteristics: Human IgG1 monoclonal antibody.
Applications:
- Cancer Therapy: Investigated for treating solid tumors that overexpress TF.
- Antibody-Drug Conjugates (ADCs): Used for targeted drug delivery in ADCs.
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