Thiol-PEG6-acid CAS:1347750-77-9, a bifunctional polyethylene glycol (PEG) derivative, features a reactive thiol group on one end and a carboxylic acid group on the other. This unique chemical structure facilitates the formation of stable, hydrophilic conjugates through thiol-disulfide exchange or thiol-maleimide click chemistry, enhancing the solubility, stability, and bioavailability of various biomolecules.
Thiol-PEG6-acid finds extensive use in pharmaceutical research and development, enabling the synthesis of PEGylated bioconjugates for targeted drug delivery and controlled release. Its versatile functional groups facilitate conjugation with proteins, peptides, and other bioactive agents, effectively improving their pharmacokinetic properties, reducing immunogenicity, and enhancing therapeutic efficacy in a wide range of clinical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
