Thalidomide-O-PEG4-Acid is a versatile molecular linker, composed of a thalidomide moiety covalently attached to a polyethylene glycol (PEG4) chain, terminated with a carboxylic acid group. This functionalized linker offers enhanced solubility, biocompatibility, and reduced immunogenicity, making it a crucial building block for pharmaceutical research and development.
Thalidomide-O-PEG4-Acid serves as a key component in the design of advanced drug conjugates and targeted therapies. By exploiting the immunomodulatory and antiangiogenic properties of thalidomide, this linker enables the creation of novel therapeutic agents with improved pharmacokinetics, enhanced tissue penetration, and reduced side effects, ultimately advancing the treatment of various diseases, including cancer and autoimmune disorders.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
