Thalidomide-O-PEG2-CH2-Ald CAS:2286368-58-7 is a type of small molecule drug that is used in the treatment of certain types of cancer and inflammatory diseases. It is composed of several functional groups, including a thalidomide group, a polyethylene glycol (PEG) spacer, and an aldehyde group.
Thalidomide is a type of immunomodulatory drug that has been shown to be effective in treating certain types of cancer, such as multiple myeloma and myelodysplastic syndromes, as well as inflammatory diseases such as rheumatoid arthritis and Crohn’s disease. The PEG spacer in Thalidomide-O-PEG2-CH2-Ald is used to improve the solubility and stability of the drug in solution, allowing it to be more easily administered to patients. The aldehyde group is important for the chemical reactivity of the compound.
In terms of its mechanism of action, Thalidomide-O-PEG2-CH2-Ald works by modulating the activity of certain immune cells in the body, particularly T cells and natural killer cells. By enhancing the activity of these cells, Thalidomide-O-PEG2-CH2-Ald can help to boost the body’s immune response to cancer cells and reduce inflammation, leading to improved outcomes for patients with cancer and inflammatory diseases.
The aldehyde group in Thalidomide-O-PEG2-CH2-Ald can also be used as a linker molecule to attach Thalidomide to other molecules, such as proteins or peptides. This allows for the creation of novel targeted drug delivery systems, which can improve the efficacy and reduce the toxicity of Thalidomide-based therapies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.