Thalidomide-O-Hexyl-Acid is an E3 ligase ligand-linker conjugate combining a Thalidomide-based cereblon ligand and an alkane linker for PROTAC technology.
Thalidomide-O-Hexyl-Acid is a novel derivative of the renowned compound thalidomide, featuring a hexyl carboxylic acid moiety. This unique functional group enhances the compound’s hydrophobicity and bioavailability, offering improved therapeutic potential and target specificity compared to its parent molecule.
The pharmaceutical research and development of Thalidomide-O-Hexyl-Acid has been focused on harnessing its immunomodulatory, anti-inflammatory, and anti-angiogenic properties. This versatile compound has demonstrated promising results in the treatment of various autoimmune diseases, inflammatory disorders, and cancer types.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
