Thalidomide-O-amido-PEG2-NHBoc CAS:1957235-73-2 is a small molecule drug composed of several functional groups, including a thalidomide group, an amide group, a polyethylene glycol (PEG) spacer, and a N-tert-butyloxycarbonyl (NHBoc) group.
Thalidomide is a type of immunomodulatory drug that has been shown to be effective in treating certain types of cancer and inflammatory diseases. The amide group in Thalidomide-O-amido-PEG2-NHBoc is used to link the thalidomide molecule to the PEG spacer, which improves the solubility and stability of the drug in solution. The PEG spacer is also important for allowing the drug to be more easily administered to patients. The NHBoc group is used to protect the amide group during the synthesis of the compound, and is removed before the drug is administered.
In terms of its mechanism of action, Thalidomide-O-amido-PEG2-NHBoc works by modulating the activity of certain immune cells in the body, particularly T cells and natural killer cells. By enhancing the activity of these cells, Thalidomide-O-amido-PEG2-NHBoc can help to boost the body’s immune response to cancer cells and reduce inflammation, leading to improved outcomes for patients with cancer and inflammatory diseases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.