Tetrazine-PEG5-Tetrazine is a symmetric bifunctional reagent. This design enables rapid and selective IEDDA reactions with strained alkenes (e.g., TCO), facilitating cross-linking and dual modification in complex biological and chemical systems. The PEG5 spacer enhances solubility, flexibility, and biocompatibility, making it ideal for advanced bioconjugation and material science applications.
Features
- Dual Tetrazine Groups: Allows simultaneous or cross-linking conjugation.
- Rapid IEDDA Reactions: High-speed, bioorthogonal reactions with strained alkenes.
- PEG5 Spacer: Enhances solubility and reduces steric hindrance.
- High Purity: ≥95% for reliable and reproducible results.
- Biocompatibility: Suitable for biological environments.
Applications
- Bioconjugation: Cross-linking or dual modification of biomolecules.
- Imaging: Development of multivalent fluorescent or radiolabeled probes.
- Diagnostics: Functionalization for biosensors and assays.
- Material Science: Synthesis of cross-linked polymers and hydrogels.
- Chemical Biology: Studies involving complex biological systems.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
