Tetrazine-PEG4-SS-Amine is a multifunctional reagent featuring a tetrazine group for rapid and selective IEDDA reactions with strained alkenes, a redox-sensitive disulfide bond for controlled cleavability, and a primary amine for versatile functionalization. The PEG4 spacer improves solubility, reduces steric hindrance, and ensures compatibility with biological and chemical systems, making it a versatile tool for a variety of applications.
Features
- Tetrazine Group: Enables fast, bioorthogonal conjugation with strained alkenes.
- Disulfide Bond: Redox-sensitive linkage for controlled cleavability.
- Primary Amine: Provides versatile functionalization options.
- PEG4 Spacer: Enhances solubility and minimizes steric interference.
- High Purity: ≥95% for reliable and reproducible results.
- Biocompatibility: Suitable for use in complex biological environments.
Applications
- Bioconjugation: Dual labeling and modification of biomolecules.
- Drug Delivery: Redox-sensitive systems for controlled release.
- Imaging: Development of fluorescent or radiolabeled probes.
- Diagnostics: Functionalization for biosensors and assay development.
- Chemical Biology: Studies in live cells and complex biological systems.
- Material Science: Functionalization of hydrogels and polymers for advanced applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
