TCO-PEG8-DBCO is a bifunctional linker consisting of trans-cyclooctene (TCO) and dibenzocyclooctyne (DBCO) moieties, connected by an 8-unit polyethylene glycol (PEG) spacer. This versatile chemical compound offers high stability, reduced aggregation, and enhanced solubility, making it an ideal choice for various bioconjugation applications.
In pharmaceutical research and development, TCO-PEG8-DBCO plays a crucial role in the design of targeted drug delivery systems and bioorthogonal chemistry. Its unique ability to facilitate rapid, selective, and biocompatible click reactions between TCO and DBCO groups, without interfering with biological processes, has revolutionized the development of novel therapeutics, diagnostics, and imaging agents.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.