TCO-PEG3-SS-PEG3-TCO is a symmetric bifunctional linker with two TCO groups for rapid, selective IEDDA reactions and a disulfide bond for redox-sensitive cleavability. The PEG3 spacers enhance solubility, reduce steric hindrance, and ensure biocompatibility, making it ideal for imaging, drug delivery, and bioconjugation applications.
Features
- Dual TCO Groups: Fast, selective bioorthogonal conjugation.
- Disulfide Bond: Redox-cleavable for controlled reversibility.
- PEG3 Spacers: Improve solubility and reaction efficiency.
- High Purity: ≥95%, reliable for sensitive applications.
- Biocompatible: Suitable for complex biological systems.
Applications
- Drug Delivery: Redox-triggered release.
- Bioconjugation: Reversible cross-linking of biomolecules.
- Imaging: Site-specific fluorescent labeling.
- Diagnostics: Development of biosensors.
- Therapeutics: Cleavable linkers in ADCs.
- Surface Functionalization: Biomolecule immobilization.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
