TCO-C3-PEG3-C3-amine (CAS 2028288-77-7, 773888-45-2) is a versatile compound widely used in pharmaceutical research. Its PEG (polyethylene glycol) chain improves solubility and biocompatibility, while the amine group enables conjugation with drugs or biomolecules for targeted applications.
Key Features:
- Structure: C₁₉H₃₆N₂O₅, Molecular Weight: 372.50 g/mol.
- Functional Groups:
- PEG Chain: Enhances solubility and facilitates cell/tissue targeting.
- Amine Group: Enables attachment to biomolecules like antibodies or peptides.
Applications:
- Drug Development:
- Creates bioconjugates or prodrugs for improved drug delivery and specificity.
- PROTACs:
- Acts as a linker for targeted protein degradation.
- Surface Functionalization:
- Forms self-assembled monolayers for drug delivery or tissue engineering.
- Click Chemistry:
- The TCO group enables bioorthogonal reactions with tetrazines.
Handling and Storage:
- Solubility: Soluble in DMSO.
- Storage: Store at -20°C, away from light and moisture.
- Precautions: Handle in a well-ventilated area with proper protective equipment.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
