t-Boc-N-Amido-PEG7-Tos
This product is a heterobifunctional PEG reagent featuring a Boc-protected amide and a tosyl leaving group on opposite ends of a PEG7 chain. This design provides orthogonal reactivity, solubility, and flexibility, making it especially valuable for stepwise synthesis, bioconjugation, and drug delivery applications.
Key Features and Benefits:
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Boc-Protected Amide: Provides acid-labile protection for selective deprotection.
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Tosyl Group: Acts as an efficient leaving group for substitution reactions.
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PEG7 Spacer: Enhances solubility, hydrophilicity, and steric flexibility.
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Orthogonal Design: Enables controlled, stepwise conjugation.
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High Purity: Ensures reproducibility in sensitive synthetic workflows.
Applications:
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Bioconjugation: Couples biomolecules through amide and substitution chemistry.
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Drug Delivery: Provides PEGylated scaffolds with controlled functionality.
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Probe Development: Builds functionalized probes for diagnostics and imaging.
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Synthetic Chemistry: Serves as an intermediate in orthogonal synthesis schemes.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); deprotect Boc groups under acidic conditions.
This product integrates a Boc-protected amide with a tosyl group in a PEG7 scaffold, specifically offering solubility and multifunctional reactivity for advanced conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
