t-Boc-N-Amido-PEG5-alcohol CAS:1404111-67-6 is a high-quality, multifunctional reagent widely employed in pharmaceutical research and development. Comprising a tertiary-butyl carbamate (t-Boc) protected amine group, an amide functional group, and a polyethylene glycol (PEG) spacer with five ethylene oxide (EO) units terminated by a hydroxyl group, this reagent exhibits exceptional versatility in bioconjugation and drug delivery applications.
The t-Boc group imparts stability, ensuring compatibility with various reaction conditions, while the amide bond confers hydrolytic stability and biocompatibility. The PEG5 spacer, a hydrophilic polymer, improves solubility, pharmacokinetics, and biodistribution of conjugated molecules. Additionally, the terminal alcohol group enables facile conjugation to a wide range of biomolecules, including proteins, peptides, and oligonucleotides.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
