t-Boc-N-Amido-PEG5-acid
This product is a PEG5 linker with a Boc-protected amide and a terminal carboxylic acid. The PEG5 spacer provides hydrophilicity, flexibility, and short-to-medium chain spacing, while the Boc group offers acid-labile protection for controlled and orthogonal conjugation workflows.
Key Features and Benefits:
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Boc-Protected Amide: Acid-labile protecting group for selective, stepwise synthesis.
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Carboxylic Acid Group: Couples efficiently with amines to form stable amide bonds.
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PEG5 Spacer: Provides balanced solubility, flexibility, and reduced steric hindrance.
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High Purity: Ensures reliable performance in sensitive workflows.
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Orthogonal Reactivity: Supports multifunctional and controlled conjugation strategies.
Applications:
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Bioconjugation: Enables precise protein, peptide, and biomolecule modification.
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Drug Delivery: PEGylated linker improves solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
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Synthetic Chemistry: Acts as a protected intermediate for orthogonal scaffold design.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain Boc and acid integrity.
This product provides compact PEG spacing with orthogonal protection, making it an especially versatile tool for conjugation, drug delivery, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
