t-Boc-N-Amido-PEG4-Tos CAS:1246999-33-6 linker contains a tosyl group and Boc-amine group. The hydrophilic PEG spacer can increase the solubility of a compound in aqueous media. The tosyl group can be easily replaced by thiol and amino group through a nucleophilic substitution. The Boc group can be deprotected under mild acidic conditions to form a free amine for amide coupling with an acid-bearing biomolecule.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.