t-Boc-N-Amido-PEG4-NHS ester CAS:859230-20-9 is a bifunctional, PEGylated crosslinker with a tertiary butyloxycarbonyl (t-Boc) protected amine on one end and an N-hydroxysuccinimide (NHS) ester on the other. This unique structure enables it to serve as a versatile linker in bioconjugation reactions, facilitating the formation of stable amide bonds with target molecules while providing water solubility and biocompatibility.
In pharmaceutical research and development, t-Boc-N-Amido-PEG4-NHS ester is widely utilized as a crosslinker in drug delivery systems, diagnostics, and targeted therapies. Its PEGylated nature imparts enhanced solubility, reduced immunogenicity, and prolonged circulation time, while the t-Boc protection and NHS ester allow for controlled conjugation to biomolecules, including proteins, peptides, and nucleic acids. This multifunctional reagent is instrumental in developing innovative therapeutics with improved pharmacokinetics and selectivity.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
