t-Boc-N-Amido-PEG36-alcohol
t-Boc-N-Amido-PEG36-alcohol is a high-purity, monofunctional polyethylene glycol derivative featuring a terminal alcohol group and a t-Boc-protected amide functionality. The long PEG36 spacer provides exceptional hydrophilicity, extended reach, and high flexibility, making it ideal for applications requiring large spatial separation or improved solubility. The t-Boc protecting group enables selective deprotection under mild acidic conditions, specifically allowing controlled conjugation steps in multi-stage syntheses.
Key Features
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t-Boc-protected amide for selective deprotection and controlled reactivity
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Terminal alcohol for versatile chemical modification or further functionalization
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Long PEG36 spacer for extended reach, reduced steric hindrance, and enhanced solubility
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High chemical purity and stability for reproducible performance
Applications
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PEGylation of biomolecules, peptides, and small molecules
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Spacer or linker in drug delivery, diagnostic, and bioconjugation systems
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Nanoparticle or surface functionalization where long hydrophilic linkers are required
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Multi-step syntheses requiring orthogonal protection strategies
Storage and Handling
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Store at –20 °C, protected from light and moisture
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Allow to equilibrate to room temperature before opening
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Avoid repeated freeze–thaw cycles to maintain integrity
This product is a monofunctional PEG linker with a terminal alcohol and a t-Boc-protected amide, connected by a long PEG36 chain specifically for high solubility, flexibility, and controlled reactivity.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
