t-Boc-N-Amido-PEG24-acid
This product is a long-chain PEG24 linker with a Boc-protected amide and a terminal carboxylic acid. The extended PEG24 spacer provides excellent hydrophilicity, flexibility, and wide spacing, while the Boc group offers acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Provides acid-labile protection for stepwise, selective synthesis.
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Carboxylic Acid Group: Couples efficiently with amines to form stable amide bonds.
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PEG24 Spacer: Ensures high solubility, reduced steric hindrance, and long-range flexibility.
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High Purity: Guarantees reproducibility in sensitive bioconjugation workflows.
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Orthogonal Reactivity: Supports controlled, multifunctional conjugation.
Applications:
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Bioconjugation: Enables precise protein, peptide, and biomolecule attachment.
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Drug Delivery: PEGylated linker enhances solubility, stability, and pharmacokinetics.
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Surface Functionalization: Functionalizes nanoparticles, polymers, or hydrogels.
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Material Science: Useful in PEGylated scaffolds for advanced material design.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve Boc and acid stability.
This product offers extended PEG spacing with dual-reactive groups, making it an especially versatile tool for orthogonal synthesis, bioconjugation, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
