t-Boc-N-Amido-PEG20-acid
This product is a long-chain PEG20 linker with a Boc-protected amide and a terminal carboxylic acid. The PEG20 spacer provides excellent solubility, flexibility, and extended spacing, while the Boc group offers acid-labile protection for orthogonal, stepwise conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Acid-labile protection for controlled, selective synthesis.
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Carboxylic Acid Group: Couples with amines to form stable amide bonds.
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PEG20 Spacer: Ensures hydrophilicity, long-range spacing, and reduced steric hindrance.
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High Purity: Supports reproducibility in advanced bioconjugation workflows.
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Orthogonal Design: Enables multifunctional conjugation and synthetic flexibility.
Applications:
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Bioconjugation: Facilitates precise attachment of proteins, peptides, and biomolecules.
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Drug Delivery: PEGylated linker improves solubility, pharmacokinetics, and stability.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
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Material Science: Useful for PEGylated scaffolds in advanced materials.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected environment.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve Boc and acid reactivity.
This product provides long PEG spacing with dual-reactive groups, making it an especially versatile reagent for bioconjugation, drug delivery, and orthogonal synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
