t-Boc-N-Amido-PEG11-Tos linker contains a tosyl group and Boc-amine group. The hydrophilic PEG spacer can increase the solubility of a compound in aqueous media. The tosyl group can be easily replaced by thiol and amino group through a nucleophilic substitution. The Boc group can be deprotected under mild acidic conditions to form a free amine for amide coupling with an acid-bearing biomolecule.
T-Boc-N-Amido-PEG11-Tos is a type of polymer used in organic chemistry. It is a polyethylene glycol (PEG) derivative with an amino group at the 11th carbon atom and a tert-butyloxycarbonyl (t-Boc) group at the nitrogen atom. This polymer is used as a linker molecule in various chemical reactions and processes.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.