t-Boc-N-amido-PEG10-NHS ester CAS:2055040-78-1 is a high-purity, bifunctional PEGylation reagent composed of a t-Boc-protected amine, a 10-unit polyethylene glycol (PEG) spacer, and an N-hydroxysuccinimide (NHS) ester. The t-Boc group provides amine protection, while the NHS ester offers efficient coupling to amines, forming stable amide linkages with various biomolecules.
In pharmaceutical research and development, t-Boc-N-amido-PEG10-NHS ester serves as a versatile bioconjugation tool for modifying peptides, proteins, and other amine-containing molecules. PEGylation improves the biocompatibility, solubility, and circulation half-life of biomolecules, thus enhancing their therapeutic potential. Additionally, t-Boc protection enables selective and controlled deprotection, facilitating further functionalization or attachment to drug delivery systems.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
