t-Boc-N-Amido-PEG1-amine
This product is a compact PEG1 linker with a Boc-protected amide and a terminal primary amine. The short PEG1 spacer provides minimal hydrophilicity and spacing, while the Boc group offers acid-labile protection for controlled, orthogonal conjugation strategies.
Key Features and Benefits:
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Boc-Protected Amide: Acid-labile protection for selective, stepwise synthesis.
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Amine Group: Couples efficiently with carboxyls, NHS esters, and other electrophiles.
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PEG1 Spacer: Compact hydrophilic chain reduces steric hindrance.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
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Orthogonal Reactivity: Supports multifunctional and controlled conjugation strategies.
Applications:
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Bioconjugation: Compact PEG linker for protein, peptide, and biomolecule conjugation.
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Drug Delivery: Enhances solubility and pharmacokinetics in therapeutic conjugates.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
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Synthetic Chemistry: Serves as an intermediate in orthogonal scaffold design.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve Boc and amine stability.
This product combines compact PEG spacing with dual reactivity, making it an especially versatile reagent for orthogonal synthesis, bioconjugation, and advanced material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
