t-Boc-N-Amido-(CH2)12-amine
This product is a high-purity alkyl linker with a t-Boc–protected amide for acid-labile deprotection and a primary amine for versatile conjugation. Its 12-carbon chain offers hydrophobic spacing, rigidity, and defined length for use in bioconjugation, surface functionalization, and drug delivery.
Key Features and Benefits
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t-Boc–Protected Amide – Acid-labile protection for orthogonal functionalization strategies.
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Primary Amine – Couples efficiently with NHS esters, activated acids, and other electrophiles.
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C12 Alkyl Spacer – Provides hydrophobic separation, structural rigidity, and defined distance between functional groups.
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High Purity – Supplied at >95% purity for reproducible performance.
Applications
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Stepwise orthogonal conjugation strategies
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Hydrophobic linker design for drug delivery and prodrugs
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Surface and polymer modification
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Spacer in multifunctional bioconjugates
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged moisture exposure to preserve functional group reactivity
This product offers a hydrophobic C12 spacer, a t-Boc–protected amide for selective deprotection, and a primary amine for conjugation, making it especially ideal for orthogonal linker strategies in bioconjugation and materials science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
