SY-9 is (QSY®-9 equivalent) a more hydrophilic version of the popular SY-7 dark quencher (QSY®-7 equivalent). This non-fluorescent acceptor dye is commonly used to prepare peptide FRET probes. The broad and intense quenching range of 500-600 nm makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in combination with dyes emitting from 500 nm to 600 nm, such as fluorescein, Oregon Green, Carboxy Rhodamine 110 (Rhodamine Green), Alexa Fluor® 488, 532, 546, 555, 568, Cy3, TAMRA and ROX dyes. SY-9 azides can react with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctynes to form stable triazoles via a copper-free “click chemistry” reaction and does not require copper catalysts or high temperatures. QSY®-9 is a registered trademark of ThermoFisher Scientific.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
