SY-7 Azide (QSY®-7 equivalent) is a non-fluorescent acceptor dye used to prepare peptide and oligonucleotide FRET probes. The broad and intense quenching range of 500-600 nm makes it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in combination with fluorochromes from 520 nm to 600 nm, such as fluorescein, Oregon green, Carboxyrhodamine 110 (Rhodamine Green), Alexa Fluor® 488, 532, 546, 555, 568, Cy3, TAMRA and ROX dyes.
SY-7 azide can react with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctynes to form stable triazoles via a copper-free “click chemistry” reaction and does not require copper catalysts or high temperatures.
QSY®-7 is a registered trademark of ThermoFisher Scientific.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
