SY-21 NHS Ester (QSY®-21 NHS Ester Equivalent, CAS: 304014-13-9)
SY-21 NHS Ester is a nonfluorescent dye, widely used in FRET applications. It quenches fluorescence over a broad range from 580 nm to 680 nm, making it ideal for use with several dyes like Fluorescein, Alexa Fluor® 568, 594, 633, 647, TAMRA, ROX, Texas Red, and Cy5.
Key Features:
- Nonfluorescent Quencher: Efficiently quenches between 580-680 nm, making it perfect for a wide variety of fluorophores.
- NHS Ester: Reacts rapidly with primary amines, such as those found on proteins (Lysines) and amine-modified oligonucleotides, forming stable covalent bonds at pH 7-9.
- Versatility: Ideal for labeling proteins, peptides, and oligonucleotides in a broad range of experiments.
Applications:
- FRET Assays: Works effectively as a nonfluorescent acceptor in FRET, quenching a broad spectrum of fluorophores.
- Molecular Probes: Easily creates quenched probes for both imaging and diagnostics in various systems.
- Bioconjugation: Efficiently labels amine-containing biomolecules, thus enabling detailed tracking and research.
Advantages:
- Strong Quenching: Covers a broad spectral range from 580-680 nm, making it highly adaptable to different needs.
- Efficient Labeling: Forms stable covalent bonds with primary amines, which provides long-lasting results across experiments.
- Wide Application: Perfect for FRET, imaging, and bioconjugation in diverse research fields.
As a result, SY-21 NHS Ester is an excellent choice for researchers in FRET, bioconjugation, and diagnostics, offering both efficient quenching and reliable labeling solutions across many scientific applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
