Sulfo-NThiol-Acetate (CAS: 152305-87-8)
Sulfo-NThiol-Acetate modifies primary amines on proteins, peptides, and other biomolecules through its sulfo-NHS ester group. It forms stable amide bonds by reacting with amines, blocking reactive sites, and preventing unwanted crosslinking during bioconjugation and protein modification.
Key Features:
- Amine-Reactive: Forms stable amide bonds with primary amines.
- Water-Soluble: Dissolves in water, eliminating the need for organic solvents.
- Crosslinking Control: Blocks amine groups to prevent polymerization.
Applications:
- Protein Modification: Protects primary amines on proteins and peptides for targeted conjugation.
- Crosslinking Prevention: Controls multi-step bioconjugation by stopping unwanted crosslinking.
Handling and Storage:
- Molecular Formula: C₆H₆NO₇SNa
- Molecular Weight: 259.17 g/mol
- Storage: Store at -20°C, away from light and moisture.
Sulfo-NThiol-Acetate is widely used in biochemical research for protein labeling, bioconjugation, and crosslinking control in aqueous environments.
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