Rhodamine-PEG-Thiol(RhB-PEG-SH), MW 5K, is a type of polyethylene glycol (PEG) derivative that contains a rhodamine dye molecule and a thiol functional group (-SH) attached to the PEG chain. Rhodamine is a fluorescent dye that emits a bright red color under excitation, making Rhodamine-PEG-Thiol a useful tool in the field of pharmaceutical research and development.
The thiol group of Rhodamine-PEG-Thiol allows for the covalent attachment of the molecule to other molecules or surfaces via disulfide bond formation. This property has made Rhodamine-PEG-Thiol a popular choice for bioconjugation applications, such as labeling and imaging of biological targets. The rhodamine dye attached to the PEG chain enables the visualization and tracking of the labeled molecules in vivo, providing valuable insights into biological processes and disease pathways.
Moreover, Rhodamine-PEG-Thiol has been utilized in drug delivery systems as a surface modifier to improve the stability and biocompatibility of the drug carriers. The dye molecule not only provides fluorescence imaging capabilities but also acts as a hydrophobic anchor, allowing for the conjugation of hydrophobic drugs to the PEG chain. The resulting conjugates exhibit improved drug solubility, prolonged circulation time, and enhanced therapeutic efficacy.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
