Rhodamine-PEG-Thiol(RB-PEG-SH), MW 3.4K with a molecular weight of 3.4K is a chemical compound belonging to the class of polyethylene glycol (PEG) derivatives. This compound contains a thiol functional group (-SH) attached to a PEG chain along with a rhodamine fluorescent dye molecule.
Rhodamine-PEG-Thiol has unique chemical properties that allow for its use in a range of biomedical applications, including drug delivery and imaging. In drug delivery, the fluorescent dye allows for tracking the movement and distribution of the drug in the body. Moreover, the thiol group allows for the covalent attachment of therapeutic agents to the PEG chain via disulfide bonds. The resulting conjugates exhibit improved stability, increased solubility, and prolonged circulation time in vivo, leading to enhanced therapeutic efficacy and reduced side effects.
In imaging applications, Rhodamine-PEG-Thiol is utilized to label cells, biomolecules, and other structures for fluorescence microscopy, flow cytometry, and other imaging techniques. The rhodamine fluorescent dye provides excellent spectral properties, allowing for high sensitivity and specificity in detecting labeled structures.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.