Rhodamine-PEG-Thiol(RhB-PEG-SH), MW 2K contains a thiol functional group (-SH) attached to a PEG chain, with a rhodamine dye molecule incorporated into the PEG chain.
The thiol group in RhB-PEG-SH allows for covalent attachment to other molecules through disulfide bond formation, which is crucial in the development of novel drug delivery systems. By conjugating RhB-PEG-SH with a therapeutic agent, such as a protein or peptide, the resulting conjugate exhibits improved stability, solubility, and pharmacokinetics, leading to enhanced therapeutic efficacy and reduced side effects.
The incorporation of the rhodamine dye into the PEG chain of RhB-PEG-SH offers additional benefits in drug delivery and imaging applications. Rhodamine is a fluorescent dye that emits a red-orange fluorescence when excited with light. This property allows for the visualization and tracking of the RhB-PEG-SH conjugate in vivo, providing valuable information on its pharmacokinetics and biodistribution.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
