PTAD-Alkyne: Overview and Applications
Product Summary
PTAD-Alkyne (CAS: 1313211-51-6) is a bioconjugation linker with a PTAD group that selectively targets tyrosine residues and an alkyne for click chemistry, especially copper-catalyzed azide-alkyne cycloaddition (CuAAC). This combination makes it perfect for stable and precise conjugation in complex environments, allowing targeted labeling and modification of proteins, peptides, and small molecules.
Key Benefits
- Tyrosine Selectivity: Specifically binds to tyrosine, avoiding other amino acids.
- Click Chemistry Ready: Alkyne group supports CuAAC for efficient, bioorthogonal conjugation.
- Stable Linkage: Forms a durable, stable connection in various biological settings.
- Versatile Use: Suitable for diverse bioconjugation and labeling needs.
Applications
- Bioconjugation and Labeling
- Enables selective labeling of tyrosine residues for tracking proteins and peptides.
- Click Chemistry
- Alkyne group allows CuAAC click chemistry with azides, providing reliable and flexible bioconjugation.
- Drug Delivery
- Supports precise attachment of therapeutic agents to biomolecules.
- Surface Functionalization
- Ideal for modifying surfaces with bioactive molecules, improving biosensor performance and diagnostic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
