Propargyl-PEG5-alcohol
This product is a bifunctional PEG5 linker with a terminal propargyl (alkyne) group and a hydroxyl group. The alkyne enables click chemistry with azides, while the hydroxyl provides a versatile handle for further functionalization, making it a useful tool in bioconjugation and material modification.
Key Features and Benefits:
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Propargyl Group: Supports CuAAC or SPAAC click chemistry with azides.
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Hydroxyl Group: Provides flexibility for further derivatization or activation.
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PEG5 Spacer: Improves solubility, flexibility, and reduces steric hindrance.
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High Purity: Ensures reliable performance in sensitive conjugation workflows.
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Versatile Reactivity: Dual functionality enables orthogonal strategies.
Applications:
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Click Chemistry: Propargyl–azide ligation for bioorthogonal labeling.
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Bioconjugation: Attach biomolecules through click reactions and hydroxyl chemistry.
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Drug Delivery: PEGylated linker to enhance solubility and pharmacokinetic behavior.
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Surface Modification: Functionalize nanoparticles, hydrogels, or polymers.
Storage and Handling:
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Storage: Store at –20 °C in a dry, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve alkyne reactivity.
This product combines click-ready alkyne functionality with a modifiable hydroxyl group, making it an especially versatile linker for synthetic, biological, and material applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
