Propargyl-PEG1-SS-PEG1-propargyl CAS:1964503-40-9 is a molecule that contains two propargyl functional groups and a disulfide linkage in between two PEG (polyethylene glycol) chains. The propargyl functional group is an alkyne, which can be used for various chemical reactions such as click chemistry. The disulfide linkage is sensitive to redox reactions, which can be cleaved in the presence of reducing agents.
In pharmaceuticals, Propargyl-PEG1-SS-PEG1-propargyl can be used as a linker to conjugate two different molecules, such as drugs and targeting agents, to improve their pharmacokinetic and pharmacodynamic properties. The PEG chains can increase the solubility and circulation time of the conjugates in the body, while the disulfide linkage can facilitate the release of the drug in the target site through redox-triggered cleavage. Overall, Propargyl-PEG1-SS-PEG1-propargyl is a versatile tool for drug delivery and development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.