Propargyl-PEG1-SS-PEG1-acid CAS:1807503-85-0 is a compound that contains several functional groups, including a propargyl group, a disulfide bond, and two polyethylene glycol (PEG) chains. In pharmaceuticals, it is often used as a linker or a spacer to connect two different molecules or to modify the surface of nanoparticles or biomolecules.
The propargyl group in Propargyl-PEG1-SS-PEG1-acid allows for further modification with other functional groups, such as azides or aldehydes, making it a versatile tool in drug development. The disulfide bond is labile and can be cleaved under reducing conditions, allowing for controlled release of drugs or other therapeutic agents. The PEG chains can improve the solubility, stability, and bioavailability of the attached molecules, as well as reduce immunogenicity and prolong circulation time in the body.
Propargyl-PEG1-SS-PEG1-acid is a valuable building block for the design and synthesis of various pharmaceuticals and biomedical materials, with potential applications in drug delivery, imaging, and tissue engineering.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
