PEG3-tetrazine is a highly reactive bioconjugation reagent used in click chemistry and bio-orthogonal applications. It features a tetrazine group that reacts rapidly with strained alkenes like TCO, enabling fast, copper-free labeling. The PEG3 spacer enhances solubility, reduces steric hindrance, and increases biocompatibility, making it perfect for complex biological systems.
Key Features:
- Tetrazine Group: Reacts quickly and selectively with TCO, ideal for precise bioconjugation and labeling.
- PEG3 Spacer: Improves solubility, reduces steric hindrance, and ensures biocompatibility in live-cell applications.
Applications:
- Live-Cell Imaging: Tags biomolecules efficiently, allowing real-time visualization in cellular environments.
- Drug Delivery: Conjugates therapeutic agents to target molecules, enhancing targeted drug delivery.
- Bioconjugation: Connects proteins, peptides, and other biomolecules through fast, specific reactions.
Benefits:
- Rapid Reactions: Provides quick and selective labeling with minimal background.
- Copper-Free: Avoids toxic catalysts, making it safe for sensitive biological work.
- Enhanced Solubility: The PEG3 chain keeps conjugates soluble and active in aqueous environments.
Storage and Handling:
- Store at -20°C in a dry, inert environment.
- Handle with standard safety precautions for reactive chemicals.
PEG3-tetrazine is ideal for use in biotechnology, pharmaceutical research, and molecular biology, offering high reactivity and versatility in bioconjugation, imaging, and targeted delivery applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
