PC Methyltetrazine-PEG4-NHS ester: Overview and Key Features
Overview
- Photo-Cleavable (PC): Enables controlled, light-triggered release of attached molecules.
- Methyltetrazine: Allows selective, efficient bioorthogonal reactions with trans-cyclooctene (TCO).
- PEG4 Chain: Enhances solubility and stability.
- NHS Group: Provides stable attachment to primary amines on biomolecules.
Key Features
- Mechanism: Light-induced cleavage for precise control over molecule release.
- Functionality: Combines photo-cleavable action with PEGylation and NHS reactivity, offering versatility in applications.
Applications
- Drug Delivery: Enables controlled, light-triggered drug release, minimizing side effects.
- Bioconjugation: Allows light-controlled attachment and release of molecules.
- Protein Labeling: Provides temporary labeling, removable with light exposure.
Advantages
- Precision: Allows exact control over molecular interactions and release.
- Stability: PEG4 chain improves solubility and stability.
Considerations
- Light Requirements: Requires precise light exposure.
- Phototoxicity: Potential for nearby molecular effects if exposed to excessive light.
PC Methyltetrazine-PEG4-NHS ester is a powerful tool for drug delivery, protein labeling, and bioconjugation in research, offering precision and control with light-activated release.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
