Norbornene-PEG1-Biotin
This product is a multifunctional PEG linker containing a norbornene group, a PEG1 spacer, and a biotin moiety. It specifically enables rapid tetrazine click chemistry and strong streptavidin binding in a compact and efficient scaffold.
Key Features and Benefits
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Norbornene Group: Reacts rapidly with tetrazines via IEDDA click chemistry.
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Biotin Moiety: Provides strong affinity binding to streptavidin and avidin systems.
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PEG1 Spacer: Offers compact length while enhancing solubility.
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Dual Reactivity: Combines click chemistry with biotin affinity capture.
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High Purity: Ensures reproducibility in sensitive bioconjugation workflows.
Applications
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Bioconjugation: Links tetrazine-modified molecules with biotin-binding systems.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides scaffolds with orthogonal click and affinity handles.
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Material Science: Functionalizes nanoparticles, polymers, and surfaces with dual groups.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates norbornene click reactivity with biotin–streptavidin affinity in a PEG1 scaffold, specifically offering compact functionality for conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
