N,N-Bis(PEG2-azide)-N-PEG2-propanoic acid
This product is a multifunctional PEG-based linker featuring two terminal azides and a carboxylic acid, connected through short PEG2 chains. The azides support bioorthogonal click chemistry, while the carboxyl group couples efficiently with amines, making this reagent highly versatile for multivalent bioconjugation and advanced material applications.
Key Features and Benefits:
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Dual Azides: Enable CuAAC or SPAAC click chemistry with alkynes.
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Carboxylic Acid Group: Couples with amines for stable amide bond formation.
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PEG2 Spacers: Provide hydrophilicity and compact flexibility.
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High Purity: Ensures reproducibility in conjugation workflows.
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Multifunctionality: Supports orthogonal and multistep bioconjugation strategies.
Applications:
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Bioconjugation: Enables dual azide labeling and carboxyl–amine coupling in one reagent.
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Click Chemistry: Provides versatile orthogonal reactivity for protein and peptide modification.
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Drug Delivery: Facilitates PEGylated linker–payload systems with enhanced solubility.
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Surface Functionalization: Functionalizes nanoparticles, hydrogels, and polymers.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain azide and acid stability.
This product offers dual azide groups and a carboxyl functionality in a compact PEG design, making it an especially powerful tool for orthogonal conjugation, drug delivery, and biomaterial modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
